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CME-CEU Program – June 23rd – Epigenetics and neurotoxicity of methamphetamine: an active killer during the opioid epidemic.

Methamphetamine use disorder (MUD) is a common neuropsychiatric disease that is associated with several short-term and long-term complications. These include cognitive deficits, memory impairments, and psychosis. There is presently no FDA-approved drug treatment for MUD. Dr. Cadet’s laboratory uses basic science approaches to develop better pharmacological therapy for these patients.

Learning Objectives:

  • To learn basic aspects of methamphetamine
    • Neurochemical effects
    • Behavioral effects
  • To learn the varied clinical presentations of methamphetamine use
    • Acute effects
    • Chronic effects
  • To learn the DSM criteria of methamphetamine use disorder 
    • Compulsive use
    • Loss of control
    • Use despite adverse consequences
  • To learn about animal models of methamphetamine use disorder in rats
    • Behavioral effects of punishment (adverse consequences)
    • Biochemical consequences
    • Epigenetic consequences

Attend Virtually or In-Person

Friday, June 23rd

Earn 1 CME/CEU

Space is limited for on-site attendees. Please RSVP by June 18th if you plan to attend on-site.

This event has already occurred, click here to watch the presentation on demand.

See what licenses are covered. 

Jean Lud CadetJean Lud Cadet, M.D. is presently a NIH Tenured Senior Investigator and the Chief of the Molecular Neuropsychiatry Research Branch and of the Molecular Neuropsychiatry Section at the National Institutes of Health/National Institute on Drug Abuse (NIDA) intramural research program (IRP). Dr. Cadet attended medical school at the Columbia University College of Physicians and Surgeons. He subsequently did psychiatry residency at the Department of Psychiatry at Columbia University and Neurology Residency at Mount Sinai Hospital in New York City. He did a post-residency fellowship at the NIMH and was an assistant professor of Neurology and Psychiatry at Columbia University before coming to NIDA IRP. Dr. Cadet has co-authored more than 500 papers, reviews, and book chapters on the molecular neurobiology of substance use disorders, cognitive aspects of cocaine and marijuana use disorders, clinical neurobiology of schizophrenia and tardive dyskinesia, as well as on mechanisms involved in models of neurodegeneration including Parkinsonism.

His work is very highly cited, with 29,691 citations and he presently has a H-index of 92. Presently, his laboratory studies the epigenetic mechanisms that potentially regulate stimulant and oxycodone-induced changes in the expression of genes in specific neuronal cells and brain regions within the reward pathways. Dr. Cadet has served on the Editorial Board of Synapse, is presently on the Editorial Board of Neurotoxicity Research, Current Neuropharmacology, International Journal of Neuropsychopharmacology, Scientific reports, and the Journal of Addictive Diseases. He is a reviewing editor for Scientific Reports and associate editor of Frontier in Public Health. Dr. Cadet is also a member of the Society for Neuroscience, ASPET, National Medical Association, Black in Neuro, Neurotoxicity Society, AMHE (Association des Medecins Haitiens a L’ Etranger), Society of Haitian Neuroscientists (SHN). He has received several awards including the NIH Director’s Award, visiting professorships including the Grass Foundation Lectureship, The Associated Medical Schools of NY for dedication and service to the promotion of Science and Health among minority youth, and the NIH Harvey J. Bullock Award.

Joint Accreditation Statement

Joint Accreditation Statement: In support of improving patient care, this activity has been planned and implemented by Amedco LLC and Galen Mental Health.  Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Amedco Joint Accreditation #4008163.

Elizabeth E. Sita, MD
Medical Director of Adult Services
Dr. Elizabeth E. Sita, MD, is a Board Certified psychiatrist specializing in the care of patients with eating disorders. She completed her undergraduate training at the University of Chicago and graduated with Highest Honors. She then earned her medical degree at Northwestern University Feinberg School of Medicine and was recognized with the Chairman’s Award for Excellence in Psychiatry. She subsequently completed residency with the Department of Psychiatry and Behavioral Sciences at McGaw Medical Center of Northwestern University, where she was elected Chief Resident and received the Resident Psychiatrist Leadership & Service Award. Upon completing her training, Dr. Sita came to Ascension Alexian Brothers Behavioral Health Hospital, where she served as Assistant Medical Director of the Center for Eating Disorders and Director of Transcranial Magnetic Stimulation Services before transitioning to lead the new inpatient eating disorder unit as Medical Director of Eating Disorder Services at Ascension Saint Joseph Hospital – Chicago. In these roles, she has cared for a multitude of adolescents and adults struggling with anorexia nervosa, bulimia nervosa, binge eating disorder, and other eating disorders as well as severe, cooccurring mood, trauma, personality, and substance use disorders. Dr. Sita has been recognized throughout her training and practice for a commitment to excellence in patient care and for her ability to engage patients in their most challenging moments. Her passions include the care of treatment-resistant eating and mood disorders as well as questions of medical capacity and end-of-life decision making. She believes that, first and foremost, human connection is key to mental health and well-being and strives to share this philosophy in each and every patient encounter. She is excited to bring her expertise to SunCloud Health as the Medical Director of Adult Services!   VIDEO: Meet Elizabeth E. Sita, MD, Medical Director of Adult Services  
Lacey Lemke, PsyD
Assistant Vice President of Clinical Services

Dr. Lacey Lemke (she/her) is a licensed clinical health psychologist with specialized expertise in the treatment of eating disorders and the practice of medical and health psychology. She completed her doctoral training in clinical psychology with a Primary Care emphasis at the Adler School of Professional Psychology. Dr. Lemke went on to complete both her predoctoral clinical internship and postdoctoral fellowship through Ascension Health, where she gained advanced training working with individuals experiencing eating disorders and self-injurious behaviors, as well as within pediatric subspecialty settings including endocrinology, neurology, and adolescent medicine.

Dr. Lemke is deeply committed to providing evidence-based, compassionate care and collaborates closely with interdisciplinary teams to ensure comprehensive treatment. Her professional mission is to support patients in achieving their fullest potential by guiding them to the most appropriate level of care and empowering them to make meaningful, sustainable progress toward improved health and well-being.